20th September 2021: Day 1
Opening Ceremony
|
16-00
16-05 16-20 |
Reading from the Qur’an
Welcome and opening remarks by President of IMARS, Prof Paul J Thornalley (QBRI/HBKU) and Chair IMARS-14 Organizing Committee, Prof Naila Rabbani (Qatar University) Welcome by Representative from Qatar National Research Fund (QNRF) |
|
16-30
|
Doha Glycation Declaration 2021- Grand challenges in glycation research Invitation for input - Prof Paul J Thornalley (QBRI/HBKU)
|
Session 1. Breakthrough Research: Unfolded protein response
|
16-45
|
Keynote Speaker: Prof Kazutoshi Mori, Lasker laureate (Kyoto University, Japan)
|
Unfolded protein response: dawn of a new field
|
Session 2. Diabetes and diabetic complications
|
17-30
|
Prof Abdul-Badi Abou-Samra (Metabolic Research Institute, Hamad Medical Corp, Qatar)
|
Qatar Diabetes Prevention Program (QDPP) – use of A1C in diabetes prevention and control
|
|
18-00
|
Prof Mark Cooper (Monash University, Australia)
|
Glycation and diabetic kidney disease
|
|
18-30
|
Prof Rayaz Malik (Weill-Cornell College of Medicine-Qatar, Qatar)
|
Glycation and diabetic neuropathy
|
|
19-00
|
Prof Ann Marie Schmidt (New York University, USA)
|
Receptor for advanced glycation endproducts (RAGE) in diabetic vascular disease
|
|
19-30
|
Prof Melinda Coughlan (Monash University, Australia)
|
Dietary factors in the initiation of diabetes and its complications
|
|
20-00
|
Day 1 - Close
|
21st September 2021: Day 2
Session 3. Glycation in food: innovation for a healthy diet
|
16-00
|
Prof Vincenzo Fogliano (University of Wageningen, The Netherlands)
|
Glycation and development of healthier foods
|
|
16-30
|
Prof Thomas Henle (Technical University of Dresden, Germany)
|
Dietary exposure to glycation adducts in food, including health benefits of Manuka honey
|
|
17-00
|
Prof Fred Tessier (University of Lille, France)
|
Metabolic transit of glycation adducts in food and physiological effects
|
|
17-30
|
Dr Gosia Teodorowicz (University of Wageningen, The Netherlands)
|
Short talk 1. Immunogenicity and allergenicity of glycated cows’ milk proteins
|
|
17-40
|
Dr Clemens Kanzler (Technische Universität Berlin, Germany)
|
Short talk 2. Structure of melanoidins formed in the Maillard reaction of methylglyoxal with L‑alanine or L‑lysine
|
|
17-50
|
Ruth Fabiola Peña-Correa (University of Wageningen, The Netherlands)
|
Short talk 3. Fluidized bed roasting drives Maillard reactions toward A more aromatic cocoa
|
Session 4. Dicarbonyl stress in obesity and diabetes (with EASD Reactive Metabolites Study Group) |
|
|
|
18-00
|
Prof Casper G. Schalkwijk (Maastricht University, The Netherlands)
|
Dicarbonyl stress in obesity and risk of type 2 diabetes
|
|
18-30
|
Prof Jacob Haus (University of Michigan, USA)
|
Dicarbonyl stress in insulin resistance and effect of exercise intervention
|
|
19-00
|
Prof Bernd Stratmann (University of the Ruhr-Bochum, Germany)
|
Dicarbonyl stress in diabetic vascular disease
|
|
19-30
|
Dr Kim Maasen (Maastricht University, The Netherlands)
|
Short talk 4. Higher habitual intake of dietary dicarbonyls is associated with higher concentrations of corresponding plasma dicarbonyls and with skin autofluorescence: the Maastricht Study
|
|
19-40
|
Prof Naila Rabbani (Qatar University, Qatar)
|
Short talk 5. Dynamics of hexokinase-2 linked glycolytic overload driving dicarbonyl stress and endothelial cell dysfunction in high glucose concentration in vitro
|
|
19-50
|
Dr Mathias Van den Eynde
(Maastricht University, The Netherlands) |
Short talk 6. Pyridoxamine reduces glycation and markers of endothelial function in a placebo-controlled intervention trial with abdominally obese individuals
|
|
20-00
|
Day 2 - Close
|
22nd September 2021: Day 3
Session 5. Glycation through the life course and aging
|
16-00
|
Prof Yasuhiko Yamamoto
(Kanazawa University, Japan) |
RAGE and maternal bonding – an expected mechanism relationship
|
|
16-30
|
Prof Vincent Monnier (Case Western Reserve University, USA)
|
Glycation in the aging lens
|
|
17-00
|
Prof Allen Taylor
(Tufts University, USA) |
Glyoxalase 1 activity declines with age in many tissues
|
|
17-30
|
Selena Le Bagge
(University of Queensland, Australia) |
Short talk 7. Short term intraperitoneal administration of mammalian cell derived human soluble receptor for advanced glycation end products (sRAGE) prevents type 1 diabetes onset in mice
|
|
17-40
|
Dr Michael Howsam
(University of Lille, France) |
Short talk 8. High hydrostatic pressure processing of human milk avoids the formation of Maillard reaction products and preserves oligosaccharides
|
23rd September 2021: Day 4
Session 7. Glycation analytics and chemistry
|
16-00
|
Prof Monika Pischetsrieder (University of Erlangen-Nuremberg, Germany)
|
Detection of dicarbonyl intermediates of glycation
|
|
17-00
|
Prof Ryoji Nagai (Tokai University, Japan)
|
Measurement of AGEs: LC-MS/MS, immunoassay and finger skin autofluorescence
|
|
17-30
|
Prof Varoujan Yaylayan (McGill University, Canada)
|
Advances in understanding of the chemical mechanisms of glycation
|
|
17-30
|
Speaker to be decided
|
Short talk 13
|
|
17-40
|
Speaker to be decided
|
Short talk 14
|
|
17-50
|
Speaker to be decided
|
Short talk 15
|
Session 8. Glycation in kidney disease, cancer and mental health
|
18-00
|
Prof Reiko Inagi (University of Tokyo, Japan)
|
Glycation in renal failure. Current state of minimizing glucose degradation products
|
|
18-30
|
Prof Matthew Vander Heiden (MIT, USA)
|
Methylglyoxal metabolism is a targetable liability of glycolytic metabolism in cancer
|
|
19-00
|
Prof Makoto Arai (University of Tokyo, Japan)
|
Glycation and mental health - anxiety, depression and schizophrenia
|
|
19-30
|
Speaker to be decided
|
Short talk 16
|
|
19-40
|
Speaker to be decided
|
Short talk 17
|
|
19-50
|
Speaker to be decided
|
Short talk 18
|
|
20-00
|
Day 4 - Close
|
24th September 2021: Day 5
Session 9. Imaging, diagnostic algorithms and therapeutics
|
16-00
|
Prof Chunyong Ding (Shanghai Jiaotong University, China)
|
Imaging of methylglyoxal in vivo in experimental models of cancer and Alzheimer’s disease
|
|
16-30
|
Prof Naila Rabbani (Qatar University, Qatar)
|
Glycation and machine learning – diagnostic algorithms for diabetes, arthritis and autism
|
|
17-00
|
Prof Paul J Thornalley (QBRI/HBKU, Qatar)
|
Glycation based therapeutics: Glo1 inducers and Glo1 inhibitors. COVID-19 repurposing
|
Session 10. Methods and models in glycation research - Qatar glycation collaboration
|
17-30
|
Dr Sowndramalingam Sankaralingam (Qatar University, Qatar)
|
Measurement of glyoxalase activities
|
|
17-45
|
Maryam Al-Motawa (QBRI/HBKU, Qatar)
|
Glo1 CNV and SNPs
|
|
18-00
|
Prof Paul J Thornalley (QBRI/HBKU, Qatar)
|
Assay of glyoxalase metabolites: methylglyoxal, S-D-lactoylglutathione and D-lactate
|
|
18-15
|
Dr Patrick Wijten (QBRI/HBKU, Qatar)
|
Quantitation of glycation adducts by stable isotopic dilution analysis LC-MS/MS
|
|
18-30
|
Prof Naila Rabbani (Qatar University, Qatar)
|
Proteomics of glycation
|
|
18-45
|
Dr Mingzhan Xue (QBRI/HBKU, Qatar)
|
Functional genomic studies of dicarbonyl stress
|
|
19-00
|
Dr Alberto da la Fuente (QBRI/HBKU, Qatar)
|
Mathematical modelling of glycation
|
|
19-15
|
Dr Hebah Al Khatib (Qatar University, Qatar)
|
Glycation in drug repurposing for COVID-19
|
|
19-30
|
Dr Essam Abdelalim (QBRI/HBKU, Qatar)
|
iPSC application in diabetes and glycation research
|
Finale and close
|
19-45
|
Prof Paul J Thornalley (IMARS President, QBRI/HBKU, Qatar)
|
|
|
20-00
|
Day 5 - Conference Close
|