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Conference Agenda

Day 1
Day 2
Day 3
Day 4
Day 5
 

20th September 2021: Day 1

Opening Ceremony

16-00

16-05
​

​16-20
​Reading from the Qur’an 

Welcome and opening remarks by President of IMARS, Prof Paul J Thornalley (QBRI/HBKU) and Chair IMARS-14 Organizing Committee, Prof Naila Rabbani (Qatar University)​​

​Welcome by Representative from Qatar National Research Fund (QNRF)
16-30
Doha Glycation Declaration 2021- Grand challenges in glycation research Invitation for input - Prof Paul J Thornalley (QBRI/HBKU) ​

Session 1. Breakthrough Research: Unfolded protein response

16-45
Keynote Speaker: Prof Kazutoshi Mori, Lasker laureate (Kyoto University, Japan)
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Unfolded protein response: dawn of a new field

Session 2. Diabetes and diabetic complications

17-30
Prof Abdul-Badi Abou-Samra (Metabolic Research Institute, Hamad Medical Corp, Qatar)
Qatar Diabetes Prevention Program (QDPP) – use of A1C in diabetes prevention and control
18-00
Prof Mark Cooper (Monash University, Australia)
Glycation and diabetic kidney disease
18-30
Prof Rayaz Malik (Weill-Cornell College of Medicine-Qatar, Qatar)
Glycation and diabetic neuropathy
19-00
Prof Ann Marie Schmidt (New York University, USA)
Receptor for advanced glycation endproducts (RAGE) in diabetic vascular disease 
19-30
Prof Melinda Coughlan (Monash University, Australia)
Dietary factors in the initiation of diabetes and its complications 
20-00
Day 1 - Close
Day 1
Day 2
Day 3
Day 4
Day 5
 

21st September 2021: Day 2

Session 3. Glycation in food: innovation for a healthy diet

16-00
Prof Vincenzo Fogliano (University of Wageningen, The Netherlands)
Glycation and development of healthier foods
16-30
Prof Thomas Henle (Technical University of Dresden, Germany)
Dietary exposure to glycation adducts in food, including health benefits of Manuka honey
17-00
Prof Fred Tessier (University of Lille, France)
Metabolic transit of glycation adducts in food and physiological effects
17-30
Dr Gosia Teodorowicz (University of Wageningen, The Netherlands)
Short talk 1. ​Immunogenicity and allergenicity of glycated cows’ milk proteins
17-40
Dr Clemens Kanzler (Technische Universität Berlin, Germany)
Short talk 2. ​Structure of melanoidins formed in the Maillard reaction of methylglyoxal with L‑alanine or L‑lysine
17-50
Ruth Fabiola Peña-Correa (University of Wageningen, The Netherlands)
Short talk 3. ​Fluidized bed roasting drives Maillard reactions toward A more aromatic cocoa

Session 4. Dicarbonyl stress in obesity and diabetes (with EASD Reactive Metabolites Study Group)

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18-00
Prof Casper G. Schalkwijk (Maastricht University, The Netherlands)​
Dicarbonyl stress in obesity and risk of type 2 diabetes
18-30
Prof Jacob Haus (University of Michigan, USA)
Dicarbonyl stress in insulin resistance and effect of exercise intervention
19-00
Prof Bernd Stratmann (University of the Ruhr-Bochum, Germany)
Dicarbonyl stress in diabetic vascular disease
19-30
Dr Kim Maasen (Maastricht University, The Netherlands)
Short talk 4. ​Higher habitual intake of dietary dicarbonyls is associated with higher concentrations of corresponding plasma dicarbonyls and with skin autofluorescence: the Maastricht Study
19-40
Prof Naila Rabbani (Qatar University, Qatar)
Short talk 5. ​Dynamics of hexokinase-2 linked glycolytic overload driving dicarbonyl stress and endothelial cell dysfunction in high glucose concentration in vitro
19-50
Dr Mathias Van den Eynde
(Maastricht University, The Netherlands)
Short talk 6. ​Pyridoxamine reduces glycation and markers of endothelial function in a placebo-controlled intervention trial with abdominally obese individuals
20-00
Day 2 - Close
Day 1
Day 2
Day 3
Day 4
Day 5

22nd September 2021: Day 3

Session 5. Glycation through the life course and aging
​16-00
​Prof Yasuhiko Yamamoto
(Kanazawa University, Japan)
RAGE and maternal bonding – an expected mechanism relationship

16-30
Prof Vincent Monnier (Case Western Reserve University, USA)
​Glycation in the aging lens

17-00
​Prof Allen Taylor
(Tufts University, USA)
​Glyoxalase 1 activity declines with age in many tissues
17-30
Selena Le Bagge
(University of Queensland, Australia)
Short talk 7. ​Short term intraperitoneal administration of mammalian cell derived human soluble receptor for advanced glycation end products (sRAGE) prevents type 1 diabetes onset in mice
17-40
Dr Michael Howsam
(University of Lille, France)
Short talk 8. ​High hydrostatic pressure processing of human milk avoids the formation of Maillard reaction products and preserves oligosaccharides
 

23rd September 2021: Day 4

Session 7. Glycation analytics and chemistry

16-00
Prof Monika Pischetsrieder (University of Erlangen-Nuremberg, Germany)
Detection of dicarbonyl intermediates of glycation
17-00
Prof Ryoji Nagai (Tokai University, Japan)
Measurement of AGEs: LC-MS/MS, immunoassay and finger skin autofluorescence
17-30
Prof Varoujan Yaylayan (McGill University, Canada)
Advances in understanding of the chemical mechanisms of glycation
17-30
Speaker to be decided
Short talk 13
17-40
Speaker to be decided
Short talk 14
17-50
Speaker to be decided
Short talk 15

Session 8. Glycation in kidney disease, cancer and mental health

18-00
Prof Reiko Inagi (University of Tokyo, Japan)
Glycation in renal failure. Current state of minimizing glucose degradation products
18-30
Prof Matthew Vander Heiden (MIT, USA)
Methylglyoxal metabolism is a targetable liability of glycolytic metabolism in cancer
19-00
Prof Makoto Arai (University of Tokyo, Japan)
Glycation and mental health - anxiety, depression and schizophrenia
19-30
Speaker to be decided
Short talk 16
19-40
Speaker to be decided
Short talk 17
19-50
Speaker to be decided
Short talk 18
20-00
Day 4 - Close
Day 1
Day 2
Day 3
Day 4
Day 5
 

24th September 2021: Day 5

Session 9. Imaging, diagnostic algorithms and therapeutics

16-00
Prof Chunyong Ding (Shanghai Jiaotong University, China)
Imaging of methylglyoxal in vivo in experimental models of cancer and Alzheimer’s disease
16-30
Prof Naila Rabbani (Qatar University, Qatar)
Glycation and machine learning – diagnostic algorithms for diabetes, arthritis and autism
17-00
Prof Paul J Thornalley (QBRI/HBKU, Qatar) 
Glycation based therapeutics: Glo1 inducers and Glo1 inhibitors. COVID-19 repurposing

Session 10. Methods and models in glycation research - Qatar glycation collaboration

17-30
Dr Sowndramalingam Sankaralingam (Qatar University, Qatar)
Measurement of glyoxalase activities 
17-45
Maryam Al-Motawa (QBRI/HBKU, Qatar)​
Glo1 CNV and SNPs
18-00
Prof Paul J Thornalley (QBRI/HBKU, Qatar)
Assay of glyoxalase metabolites: methylglyoxal, S-D-lactoylglutathione and D-lactate
18-15
Dr Patrick Wijten (QBRI/HBKU, Qatar)
Quantitation of glycation adducts by stable isotopic dilution analysis LC-MS/MS 
18-30
Prof Naila Rabbani (Qatar University, Qatar)
Proteomics of glycation
18-45
Dr Mingzhan Xue (QBRI/HBKU, Qatar)
Functional genomic studies of dicarbonyl stress 
19-00
Dr Alberto da la Fuente (QBRI/HBKU, Qatar)
Mathematical modelling of glycation
19-15
Dr Hebah Al Khatib (Qatar University, Qatar)
Glycation in drug repurposing for COVID-19
19-30
Dr Essam Abdelalim (QBRI/HBKU, Qatar)
iPSC application in diabetes and glycation research

Finale and close

19-45
Prof Paul J Thornalley (IMARS President, QBRI/HBKU, Qatar) 
  • Grand challenges in glycation research – Doha Glycation Declaration 2021
  • IMARS Society – change of President
20-00
Day 5 - Conference Close
Day 1
Day 2
Day 3
Day 4
Day 5
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