20th September 2021: Day 1
Opening Ceremony
Times in AST (Arabia Standard Time). For timing in other time zones, see IMARS landing page
16-00
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Reading from the Qur'an
Mr Ammar Humaidi (4th Year medical student, College of Medicine, Qatar University) |
16-05
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Welcome and opening remarks
Prof Paul J Thornalley
(QBRI/HBKU, Qatar), President of IMARS
Prof Naila Rabbani
(Qatar University, Qatar) Chair IMARS-14 Organizing Committee
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16-20
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Welcome by our sponsors, Qatar National Research Fund (QNRF)
Dr Fatemeh Darakhshan (Program Manager, Biomedical Science & Health, QNRF)
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16-30
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Doha Glycation Declaration 2021 - Grand challenges in glycation research Call for input
Prof Paul J Thornalley (QBRI/HBKU, Qatar)
Draft
"We, the undersigned - glycation researchers at IMARS-14, identify the following areas for priority advance in glycation research:
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Session 1. Keynote speaker - Breakthrough Research: Unfolded protein response
Moderators: Prof Naila Rabbani (Qatar University, Qatar) and Prof Paul J Thornalley (QBRI/HBKU)
16-45
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Prof Kazutoshi Mori, Lasker laureate
(Kyoto University, Japan) |
Dynamics of function and regulation of the endoplasmic reticulum
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Session 2. Diabetes and diabetic complications
Moderators: Prof Naila Rabbani (Qatar University, Qatar) and Prof Shahrad Taheri (Weill-Cornell College of Medicine-Qatar & Hamad Medical Corporation, Qatar)
17-30
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Prof Abdul-Badi Abou-Samra
(Metabolic Research Institute, Hamad Medical Corporation, Qatar) |
Insulin sensitivity and pre-Diabetes in Qatar
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18-00
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Prof Mark Cooper
(Monash University, Australia) |
Transactivation of the Receptor for Advanced Glycation Endproducts mediating pro-inflammatory signaling in diabetes
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18-30
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Prof Rayaz Malik
(Weill-Cornell College of Medicine-Qatar, Qatar) |
Challenging the dogma in diabetic neuropathy
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19-00
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Prof Ann Marie Schmidt
(New York University, USA) |
RAGE/DIAPH1: Molecular mechanisms and therapeutic strategies in obesity and diabetic complications
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19-30
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Assoc Prof Melinda Coughlan
(Monash University, Australia) |
Targeting the gut to reduce AGE-mediated damage in diabetes
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20-00
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Day 1 - Plenary session Close
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21st September 2021: Day 2
15-00
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Pre-session on-line poster discussion session 1 (Posters 1 - 22) |
Session 3. Glycation in food: innovation for a healthy diet
Moderators: Prof Hiba Bawadi (Qatar University, Qatar) and Prof Monika Pischetsrieder (University of Erlangen-Nuremberg, Germany)
16-00
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Prof Vincenzo Fogliano
(University of Wageningen, The Netherlands) |
Glycation and development of healthier foods
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16-30
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Prof Thomas Henle
(Technical University of Dresden, Germany) |
Manuka honey and its unique glycation chemistry
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17-00
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Prof Fred Tessier
(University of Lille, France) |
Does the quote “Sola dosis facit venenum" apply to the physiological effects of glycation adducts?
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Short talks
17-30
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Dr Gosia Teodorowicz
University of Wageningen, The Netherlands) |
Short talk 1. Immunogenicity and allergenicity of glycated cows’ milk proteins
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17-40
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Dr Clemens Kanzler
(Technische Universität Berlin, Germany) |
Short talk 2. Structure of melanoidins formed in the Maillard reaction of methylglyoxal with L‑alanine or L‑lysine
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17-50
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Ruth Fabiola Peña-Correa
(University of Wageningen, The Netherlands) |
Short talk 3. Fluidized bed roasting drives Maillard reactions toward A more aromatic cocoa
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Moderators: Prof Reiko Inagi (University of Tokyo, Japan) and Prof Vincent Monnier (Case Western Reserve University, USA)
18-00
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Prof Casper G. Schalkwijk
(Maastricht University, The Netherlands) |
Methylglyoxal stress in obesity and (risk of) type 2 diabetes
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18-30
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Prof Jacob Haus
(University of Michigan, USA) |
Dicarbonyl stress in insulin resistance and effects of exercise interventions
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19-00
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Prof Bernd Stratmann
(University of the Ruhr-Bochum, Germany) |
Dicarbonyl stress in diabetic vascular disease
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Short talks
19-30
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Dr Kim Maasen
(Maastricht University, The Netherlands) |
Short talk 4. Higher habitual intake of dietary dicarbonyls is associated with higher concentrations of corresponding plasma dicarbonyls and with skin autofluorescence: the Maastricht Study
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19-40
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Prof Naila Rabbani
(Qatar University, Qatar) |
Short talk 5. Dynamics of hexokinase-2 linked glycolytic overload driving dicarbonyl stress and endothelial cell dysfunction in high glucose concentration in vitro
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19-50
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Dr Mathias Van den Eynde
(Maastricht University, The Netherlands) |
Short talk 6. Pyridoxamine reduces glycation and markers of endothelial function in a placebo-controlled intervention trial with abdominally obese individuals
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20-00
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Day 2 - Plenary session close
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20-00 - 20-30
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Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)
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22nd September 2021: Day 3
15-00
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Pre-session on-line poster discussion session 2 (Posters 23 - 44) |
Session 5. Glycation through the life course - from maternal bonding to aging
Moderators: Prof Ann Marie Schmidt (New York University, USA) and Assoc Prof Melinda Coughlan (Monash University, Australia)
16-00
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Prof Yasuhiko Yamamoto
(Kanazawa University, Japan) |
RAGE and maternal bonding – an expected mechanism relationship
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16-30
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17-00
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Short talks
17-30
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Selena Le Bagge
(University of Queensland, Australia) |
Short talk 7. Short term intraperitoneal administration of mammalian cell derived human soluble receptor for advanced glycation end products (sRAGE) prevents type 1 diabetes onset in mice
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17-40
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Dr Michael Howsam
(University of Lille, France) |
Short talk 8. High hydrostatic pressure processing of human milk avoids the formation of Maillard reaction products and preserves oligosaccharides
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17-50
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Armand Linkens
(Maastricht University, The Netherlands) |
Short talk 9. Effect of a 4-week diet low and high in AGEs on insulin sensitivity and secretion, vascular function, and markers of low-grade inflammation and endothelial dysfunction of abdominally obese individuals – preliminary results from the deAGEing trial
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Session 6. Glycation in plants - physiology, function and food security. Glycation research in the response to the COVID-19 pandemic
Glycation in plants - physiology, function and food security
Moderators: Dr Talaat Youssef (Environmental Science Center, Qatar University, Qatar) and Prof Vincenzo Fogliano (University of Wageningen, The Netherlands)
18-00
|
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18-30
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Prof Andrej Frolov
(St. Petersburg State University, Russia & Leibnitz Institute of Plant Biochemistry, Halle, Germany) |
Glycation of plant proteins – a step forward to understanding the biological role
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19-00
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Prof Sneh L. Singla‐Pareek
(International Centre for Genetic Engineering and Biotechnology, India) |
Glyoxalases: the antidote for methylglyoxal and plant stress
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Short talks
19-30
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Dr Alena Soboleva
(St. Petersburg State University, Russia & Leibnitz Institute of Plant Biochemistry, Halle, Germany) |
Short talk 10. Drought-related changes in pea root nodule metabolome
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Glycation research in the response to the COVID-19 pandemic
19-40
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Israa Elbashir
(Qatar University, Qatar) |
Short talk 11. Evaluation of MG antiviral activity against SARS-CoV-2
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19-50
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Prof Paul J Thornalley
(QBRI/HBKU, Qatar) |
Short talk 12. Anti-inflammatory activity of glyoxalase-1 inducer, trans-resveratrol and hesperetin, in human small airway epithelial cell primary cultures support application for prevention of COVID-19.
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20-00
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Day 3 - Plenary session close
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20-00 - 20-30
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Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)
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23rd September 2021: Day 4
15-00
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Pre-session on-line poster discussion session 3 (Posters 45 - 67) |
Session 7. Glycation analytics and chemistry
Moderators: Prof Fred Tessier (University of Lille, France) and Prof Thomas Henle (Technical University of Dresden, Germany)
16-00
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Prof Monika Pischetsrieder
(University of Erlangen-Nuremberg, Germany) |
Detection of reactive carbonyl intermediates of glycation
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16-30
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Prof Ryoji Nagai
(Tokai University, Japan) |
Measurement of AGEs: LC-MS/MS, immunoassay and finger skin autofluorescence
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17-00
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Prof Varoujan Yaylayan
(McGill University, Canada) |
Mechanochemistry: Maillard Reaction “Through the Looking Glass”
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Short talks
17-30
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Prof Marcus Glomb
(Martin-Luther University of Halle, Germany) |
Short talk 13. Update to the N6-carboxymethyl lysine story
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17-40
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Prof Michael Hellwig
(Technical University Braunschweig & Technical University Dresden, Germany) |
Short talk 14. Enzymatic decarboxylation of Nε-carboxymethyl-lysine by ornithine decarboxylases reveals underground metabolism as a route for in vivo processing of glycated amino acids
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17-50
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Dr Alberto Fiore
(University of Abertay, United Kingdom) |
Short talk 15. Polyphenols as trapping agents of reactive carbonyl species: new strategy to reduce harmful compounds in e-cigarette emissions
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Session 8. Glycation in kidney disease, cancer and mental health
Moderators: Dr Mariam Al-Muftah (QBRI/HBKU) and Prof Casper G. Schalkwijk (Maastricht University, The Netherlands)
18-00
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Prof Reiko Inagi
(University of Tokyo, Japan) |
Organelle stress and metabolic derangement in kidney disease
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18-30
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Prof Matthew Vander Heiden
(MIT, USA) |
Methylglyoxal metabolism is a targetable liability of glycolytic metabolism in cancer
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19-00
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Prof Makoto Arai
(University of Tokyo, Japan) |
Glycation and mental health: schizophrenia
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Short talks
19-30
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Prof Paul J Beisswenger
(Dartmouth University, USA) |
Short talk 16. Multiple outcome studies confirm predictive value of AGEs for diabetic kidney disease
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19-40
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Dr Muhanad Alhujaily
(Bisha University, Kingdom of Saudi Arabia) |
Short talk 17. The spliceosome is a target for glycation in methylglyoxal-induced apoptosis and is shielded by glyoxalase 1 in multidrug resistance-linked cancer chemotherapy
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19-50
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Leigh Donnellan
(University of South Australia, Australia) |
Short talk 18. Methylglyoxal targets proteins involved in mitotic fidelity
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20-00
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Day 4 - Plenary session close
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20-00 - 20-30
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Virtual Trade Exhibition (Exhibitors available on-line for inquiries and discussion)
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24th September 2021: Day 5
Session 9. Imaging, diagnostic algorithms and therapeutics
Moderators: Prof Ryoji Nagai (Tokai University, Japan) and Prof Bernd Stratmann (University of the Ruhr-Bochum, Germany)
16-00
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Prof Chunyong Ding
(Shanghai Jiaotong University, China) |
Design and synthesis of near-infrared fluorescent probe targeting tumor metabolite methylglyoxal for visualization study
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16-30
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Prof Naila Rabbani
(Qatar University, Qatar) |
Glycation and machine learning – diagnostic algorithms for diabetes, arthritis and autism
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17-00
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Prof Paul J Thornalley
(QBRI/HBKU, Qatar) |
Glycation based therapeutics: Glo1 inducers and Glo1 inhibitors. COVID-19 repurposing
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Session 10. Methods and models in glycation research - Qatar glycation collaboration
Moderators: Professor Naila Rabbani (Qatar University, Qatar) and Professor Paul J Thornalley (QBRI/HBKU, Qatar)
17-30
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Dr Sowndramalingam Sankaralingam
(Qatar University, Qatar) |
Measurement of glyoxalase activities
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17-45
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Maryam Al-Motawa
(QBRI/HBKU, Qatar) |
Genetics of glycation - glycated hemoglobin, GLO1 single nucleotide polymorphisms and copy number variation
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18-00
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Prof Paul J Thornalley
(QBRI/HBKU, Qatar) |
Assay of glyoxalase metabolites: methylglyoxal, S-D-lactoylglutathione and D-lactate
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18-15
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Prof Naila Rabbani
(Qatar University, Qatar) |
Quantitation of glycation adducts by stable isotopic dilution analysis LC-MS/MS
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18-30
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Dr Patrick Wijten
(QBRI/HBKU, Qatar) |
Proteomics of glycation
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18-45
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Dr Mingzhan Xue
(QBRI/HBKU, Qatar) |
Application of functional genomics in studies of dicarbonyl stress
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19-00
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Dr Alberto da la Fuente
(QBRI/HBKU, Qatar) |
Mathematical modelling of dicarbonyl stress
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19-15
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Dr Hebah Al Khatib
(Qatar University, Qatar) |
Glycation in drug repurposing for COVID-19
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19-30
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Dr Essam Abdelalim
(QBRI/HBKU, Qatar) |
Inducible pluripotent stem cells (iPSCs) application in diabetes and glycation research
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Finale and close
19-45
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Prof Paul J Thornalley
(IMARS President, QBRI/HBKU, Qatar) |
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20-00
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Day 5 - Conference Close
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IMARS-14 Screenshots
Session 1. Professor Kazutoshi Mori delivers keynote presentation on the Unfolded Protein Response
Session 2. Top left - Professor Abul-Badi Abou Samra (Hamad Medical Corporation, Qatar; center) presents on the Qatar Diabetes Prevention Programme, with moderators Professor Naila Rabbani (Qatar University, Qatar; left) and Professor Shahrad Taheri (Hamad Medical Corporation, Qatar; right). Top middle - Professor Mark Cooper (Monash University, Australia). Top right - Professor Rayaz Malik (Weill-Cornell College of Medicine-Qatar, Qatar) with moderators. Bottom left - Prof Ann Marie Schmidt (New York University, USA) presents on RAGE. Bottom right - Associate Professor Melinda Coughlan
(Monash University, Australia) presenting on Targeting the gut to reduce AGE-mediated damage in diabetes.
(Monash University, Australia) presenting on Targeting the gut to reduce AGE-mediated damage in diabetes.
Session 3. Left - Presentation by Professor Vincenzo Fogliano (University of Wageningen, The Netherlands); Center - Presentation by Professor Thomas Henle (Technical University of Dresden, Germany); and Right - Professor Fred Tessier (University of Lille, France)
Session 4. Left - Professor Casper G. Schalkwijk (Maastricht University, The Netherlands); Center - Professor Jacob Haus (University of Michigan, USA); and Right - Professor Bernd Stratmann (University of the Ruhr-Bochum, Germany)
Session 5. Left - Professor Yasuhiko Yamamoto (Kanazawa University, Japan); Middle - Professor Vincent Monnier (Case Western Reserve University, USA); and Right - Professor Allen Taylor (Tufts University, USA)
Session 6. Professor Chikahiro Miyake (Kobe University, Japan), Professor Andrej Frolov (St. Petersburg State University, Russia & Leibnitz Institute of Plant Biochemistry, Halle, Germany) and Dr Charanpreet Kaur (International Centre for Genetic Engineering and Biotechnology, India)
More conference screenshots to follow.
More conference screenshots to follow.
Session 7. Left - Prof Monika Pischetsrieder (University of Erlangen-Nuremberg, Germany; center) with moderators, Professor Fred Tessier left) and Professor Thomas Henle (right); Center - Professor Ryoji Nagai (Tokai University, Japan); Right - Prof Varoujan Yaylayan (McGill University, Canada)
Session 8. Left - Presenter Professor Reiko Inagi (University of Tokyo, Japan); Middle - Presenter Professor Matthew Vander Heiden (MIT, USA; middle) with moderators Dr Mariam Al-Muftah (QBRI/HBKU, left) and Professor Casper G. Schalkwijk (Maastricht University, The Netherlands; right); Right - Short talk presenter Dr Muhanad Alhujaily (Bisha University, KSA)
Session 9. Left - Professor Chunyong Ding (Shanghai Jiaotong University, China); Middle - Professor Naila Rabbani (Qatar University, Qatar); and Right - and Professor Paul J Thornalley (QBRI/HBKU, Qatar)
Session 10. From Left - Professor Paul J Thornalley (QBRI/HBKU, Qatar); Professor Naila Rabbani (Qatar University, Qatar); Dr Mingzhan Xue, Dr Patrick Wijten and Dr Essam Abdelalim (QBRI/HBKU, Qatar).
Finale. Top left - Closing words and thanks from IMARS out-going President, Professor Paul J Thornalley. Welcome for new joint Presidents: Top middle - Professor Casper G. Schalkwijk and Top Right - Professor Fred Tessier. Bottom - Announcement of IMARS-15!
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